Dietary Supplementation with Moringa oleifera and Turmeric Synergistically Enhances Immuno-Antioxidant Status and Alleviates Heat Stress in Shami Goats | ||
| مجله علوم و صنایع غذایی ایران | ||
| Volume 22, Issue 164, 1404, Pages 180-193 PDF (434.15 K) | ||
| Document Type: مقاله پژوهشی | ||
| DOI: 10.48311/fsct.2026.118562.83007 | ||
| Authors | ||
| Rawaa Mohhamed Obiad* ; Dunia Hisham taha; Doaa hassan Abdalwahab; Mohammed Ahmed | ||
| University of Tikrit, College of Education for Pure science, Department of life sciences | ||
| Abstract | ||
| The current study aimed at determining whether dietary supplementation with the Moringa oleifera leaf extract (MOLE) and turmeric would mitigate against the adverse effects of heat stress on immune functions and the oxidative status of Shami goats. Twenty-four adult female Shami goats Shami goats were randomly assigned four equal groups and exposed to a natural heat stress (THI: 82-92) over 60 days. The control group was served with the basal diet whereas the treatment groups were served with the basal diet supplemented with 3% MOLE, 2% turmeric and 1.5% MOLE plus 1% turmeric. Antioxidant enzymes, inflammatory cytokines, lymphocyte populations, immunoglobulins and heat shock proteins were measured by taking blood samples at biweekly intervals. The combined supplementation group had significant improvements on all the measured parameters. The antioxidant enzyme activities were higher and the SOD activity was higher (93.40 U/mL) compared to controls (68.25 U/mL). The pro inflammatory cytokines were reduced significantly -IL-6 reduced to 22.1 pg/mL and TNF-a reduced to 18.4 pg/mL. The proportion of CD4+/CD8+ increased to 1.8, which is a good sign of cellular immunity. The expression of heat shock protein 70 was 2.3-fold larger, whereas the concentration of IgG was raised by 12.3 to 16.8 mg/mL. These results indicate that Moringa and turmeric supplementation can be effective as a natural approach to beat heat stress in goats through improvement of antioxidant defenses, attenuation of inflammation and maintenance of immune functions. | ||
| Keywords | ||
| Heat stress; Moringa oleifera; Curcumin; Oxidative stress; Cytokines; Immunity; Damascus goats | ||
| References | ||
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