pishgooei, Fateme, Mehrazin, Saeed, Esmaeilpour, Khadijeh (2022). Impact of Maternal Separation on Long-Term Potentiation and Synaptic Plasticity: Insights from Rodent Models. , 25(3), 36-39.
Fateme pishgooei; Saeed Mehrazin; Khadijeh Esmaeilpour. "Impact of Maternal Separation on Long-Term Potentiation and Synaptic Plasticity: Insights from Rodent Models". , 25, 3, 2022, 36-39.
pishgooei, Fateme, Mehrazin, Saeed, Esmaeilpour, Khadijeh (2022). 'Impact of Maternal Separation on Long-Term Potentiation and Synaptic Plasticity: Insights from Rodent Models', , 25(3), pp. 36-39.
pishgooei, Fateme, Mehrazin, Saeed, Esmaeilpour, Khadijeh Impact of Maternal Separation on Long-Term Potentiation and Synaptic Plasticity: Insights from Rodent Models. , 2022; 25(3): 36-39.

Impact of Maternal Separation on Long-Term Potentiation and Synaptic Plasticity: Insights from Rodent Models

Pathobiology Reserach
Article 6, Volume 25, Issue 3, 2022, Pages 36-39    PDF (73.39 K)
Document Type: Analytic Review
Authors
Fateme pishgooei; Saeed Mehrazin; Khadijeh Esmaeilpour*
Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
Abstract
Maternal separation (MS) is a well-characterized model of early life stress, based on the postnatal disruption of the mother-infant interaction. Studies on rodents have demonstrated that MS, as an early adverse life event, leads to spatial memory deficits and lasting changes in brain plasticity. Here, we review data from animal studies regarding the impact of MS on long-term potentiation (LTP). Evidence shows that animal models are useful for evaluating the effects of MS on LTP. Overall, studies suggest that MS impairs LTP.
Keywords
Maternal separation; long-term potentiation; LTP; MS; Synaptic Plasticity; Brain; hippocampal granule cells; memory; BDNF; NMDA
References
Statistics
Article View: 80
PDF Download: 46
Statistics
Number of Journals45
Number of Issues2,171
Number of Articles24,674
Article View24,437,051
PDF Download17,551,648