Oloruntola, Olugbenga David, Falowo, Andrew Bamidele, Ayodele, Simeon Olugbenga, Olarotimi, Olumuyiwa Joseph, Adeyeye, Samuel Adebowale, Osowe, Clement Oluwafemi, Oloruntola, Deborah Adebukola, Gbore, Francis Ayodeji, Oladebeye, Fehintoluwa Stellamaris (2025). Juglans regia Kernel Powder Supplementation in Broiler Chickens Fed Aflatoxin-Contaminated Diets: Effect on Growth, Serum Chemistry Indices, Immunoglobulin and Pro-Inflammatory Cytokines. , 27(2), 301-312. doi: 10.22034/JAST.27.2.301
Olugbenga David Oloruntola; Andrew Bamidele Falowo; Simeon Olugbenga Ayodele; Olumuyiwa Joseph Olarotimi; Samuel Adebowale Adeyeye; Clement Oluwafemi Osowe; Deborah Adebukola Oloruntola; Francis Ayodeji Gbore; Fehintoluwa Stellamaris Oladebeye. "Juglans regia Kernel Powder Supplementation in Broiler Chickens Fed Aflatoxin-Contaminated Diets: Effect on Growth, Serum Chemistry Indices, Immunoglobulin and Pro-Inflammatory Cytokines". , 27, 2, 2025, 301-312. doi: 10.22034/JAST.27.2.301
Oloruntola, Olugbenga David, Falowo, Andrew Bamidele, Ayodele, Simeon Olugbenga, Olarotimi, Olumuyiwa Joseph, Adeyeye, Samuel Adebowale, Osowe, Clement Oluwafemi, Oloruntola, Deborah Adebukola, Gbore, Francis Ayodeji, Oladebeye, Fehintoluwa Stellamaris (2025). 'Juglans regia Kernel Powder Supplementation in Broiler Chickens Fed Aflatoxin-Contaminated Diets: Effect on Growth, Serum Chemistry Indices, Immunoglobulin and Pro-Inflammatory Cytokines', , 27(2), pp. 301-312. doi: 10.22034/JAST.27.2.301
Oloruntola, Olugbenga David, Falowo, Andrew Bamidele, Ayodele, Simeon Olugbenga, Olarotimi, Olumuyiwa Joseph, Adeyeye, Samuel Adebowale, Osowe, Clement Oluwafemi, Oloruntola, Deborah Adebukola, Gbore, Francis Ayodeji, Oladebeye, Fehintoluwa Stellamaris Juglans regia Kernel Powder Supplementation in Broiler Chickens Fed Aflatoxin-Contaminated Diets: Effect on Growth, Serum Chemistry Indices, Immunoglobulin and Pro-Inflammatory Cytokines. , 2025; 27(2): 301-312. doi: 10.22034/JAST.27.2.301

Juglans regia Kernel Powder Supplementation in Broiler Chickens Fed Aflatoxin-Contaminated Diets: Effect on Growth, Serum Chemistry Indices, Immunoglobulin and Pro-Inflammatory Cytokines

Journal of Agricultural Science and Technology
Article 4, Volume 27, Issue 2, 2025, Pages 301-312    PDF (5.06 M)
Document Type: Original Research
DOI: 10.22034/JAST.27.2.301
Authors
Olugbenga David Oloruntola* 1; Andrew Bamidele Falowo1; Simeon Olugbenga Ayodele2; Olumuyiwa Joseph Olarotimi1; Samuel Adebowale Adeyeye3; Clement Oluwafemi Osowe4; Deborah Adebukola Oloruntola5; Francis Ayodeji Gbore1; Fehintoluwa Stellamaris Oladebeye1
1Department of Animal Science, Adekunle Ajasin University, Akungba Akoko, Nigeria.
2Department of Agricultural Technology, The Federal Polytechnic, Ado Ekiti, Nigeria.
3Department of Animal Health and Production Technology, Federal College of Agriculture, Akure, Nigeria.
4Department of Animal Production and Health, The Federal University of Technology, Akure, Nigeria.
5Department of Medical Laboratory Science, University of Medical Sciences, Ondo City, Nigeria.
Abstract
This study aimed to investigate the impact of Juglans regia Kernel Powder (JKP) on broiler chickens subjected to Aflatoxin (AF)-contaminated diets during a 42-day feeding trial conducted in February and March 2022. A total of 240 one-day-old broiler chickens were divided into four dietary groups: Diet 1 (Control), Diet 2 (0.5 mg kg-1 AF), Diet 3 (0.5 mg kg-1 AF+250 mg kg-1 JKP), and Diet 4 (0.5 mg kg-1 AF+500 mg kg-1 JKP). Birds on Diet 2 exhibited a significantly lower (P= 0.01) relative growth rate compared to the other diets. JKP supplementation at 250 mg kg-1 (Diet 3) and 500 mg kg-1 (Diet 4) mitigated the negative impact of AF on growth. Birds on Diet 2 showed significantly lower (P= 0.01) serum concentrations of total protein, albumin, and globulin compared to those on Diets 1, 3, and 4. Elevated levels of Aspartate aminotransferase (AST) and creatinine in Diet 2 indicated liver and kidney damage. Alanine Transaminase (ALT) concentrations in Diet 2 were higher (P= 0.01) than Diets 1 and 4. Birds fed diet 2 had lower glucose levels (P= 0.01) than diets 1 and 4. IgA levels in birds fed Diet 2 were lower (P= 0.03) than those in the birds fed Diet 4. Birds fed diet 2 had considerably (P< 0.05) lower IgE and IgG levels than birds fed diets 1 and 4. Nuclear Factor Kappa B (NFK B) was higher (P= 0.01) in birds fed Diet 2 compared to other diets. Interleukin 6 (IL 6) concentration was significantly (P= 0.01) higher in the birds fed Diet 2 than in the other diets. A recommended dietary supplementation of 250 mg kg-1 JKP is suggested based on the observed ameliorative effects.
Keywords
Botanicals; Dietary supplementation; Immunity; Inflammation
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