Jamali, Somayeh, Emtiazjoo, Mozhgan, Toolabee, Ladan, Zeinali, Sirous, Zeinali, Sirous, keypour, Sepideh, Sardari, Soroush, Ramezani, Ali, Azarang, Parisa (2009). Antibacterial effect of the Persian Gulf sea cucumber Holoturia. SP extracts on three strain of Escherichia coli. , 12(2), 37-49.
Somayeh Jamali; Mozhgan Emtiazjoo; Ladan Toolabee; Sirous Zeinali; Sirous Zeinali; Sepideh keypour; Soroush Sardari; Ali Ramezani; Parisa Azarang. "Antibacterial effect of the Persian Gulf sea cucumber Holoturia. SP extracts on three strain of Escherichia coli". , 12, 2, 2009, 37-49.
Jamali, Somayeh, Emtiazjoo, Mozhgan, Toolabee, Ladan, Zeinali, Sirous, Zeinali, Sirous, keypour, Sepideh, Sardari, Soroush, Ramezani, Ali, Azarang, Parisa (2009). 'Antibacterial effect of the Persian Gulf sea cucumber Holoturia. SP extracts on three strain of Escherichia coli', , 12(2), pp. 37-49.
Jamali, Somayeh, Emtiazjoo, Mozhgan, Toolabee, Ladan, Zeinali, Sirous, Zeinali, Sirous, keypour, Sepideh, Sardari, Soroush, Ramezani, Ali, Azarang, Parisa Antibacterial effect of the Persian Gulf sea cucumber Holoturia. SP extracts on three strain of Escherichia coli. , 2009; 12(2): 37-49.

Antibacterial effect of the Persian Gulf sea cucumber Holoturia. SP extracts on three strain of Escherichia coli

Pathobiology Reserach
Article 4, Volume 12, Issue 2, 2009, Pages 37-49    PDF (802.83 K)
Authors
Somayeh Jamali1; Mozhgan Emtiazjoo* 2; Ladan Toolabee3; Sirous Zeinali4; Sirous Zeinali4; Sepideh keypour2; Soroush Sardari5; Ali Ramezani6; Parisa Azarang7
1Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
2Department of Marine Biology, Faculty of Marine Sciences and Technology, Azad Islamic University, North Tehran Branch Tehran, Iran
3Department of Molecular Medicine, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
4Department of Molecular Medicine, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran Department of Genetics, Kawsar Human Genetics Research Center, Tehran, Iran
5Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
6Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, , Iran
7of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
Abstract
Objective: Sea cucumber is a traditional food and medical item and has been reported to exhibit Antioxidant, antifungal, anti tumoral and antibacterial bioactivity. The objective of this study is to describe the antibacterial activity of 4 extracts of Holoturia. Sp (sea cucumber), collected from Hengam Island of Persian Gulf.
Materials and Methods: Methanol, hexane, aqueous and chloroform extracts from body wall tissue of the sea cucumber were screened for antibacterial activity against three strains of Escherichia coli Top 10 F´, TG1 and K12 using disc diffusion and broth microdilution tests methods.
Result: The growth of all these strains were inhibited using concentration from 0.78 to 100 mg/ml of methanol, hexan and chloroform extracts. Among the extracts just methanol and chloroform with 100 mg/ml had bactericidal effect on TG1 and K12 strains. On the other hand, Aqueous extract had induced growth in of the all strains.
Conclusion: The results suggest the possibility of applying sea cucumber as source of potential anti bacterial agents, whose compounds can be good candidates to make antibiotic products.
Keywords
Antibacterial; Sea cucumber; Disc diffusion; Broth microdilution tests
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