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Volume 2, Issue 1 (3-2014)
Abstract
Aim: Regarding the high prevalence of breast cancer among the Iranian women and lack of attention to mammography screening, planning the behavior promotion interventions would be practicable through determining the barriers of conducting mammography screening behavior. The purpose of this study was determining the barriers of conducting breast cancer mammography screening among the women over 40 years. Methods: The participants of this crass-sectional study consisted of 294 over 40-years old women in Arak-Iran who completed the questionnaire of mammography barriers. The questionnaire used was based on Champion's revised Health Belief Model Scale (CHBMS). Sampling was based on the population. All hygiene officers of the Health and Cure Centers of Arak were asked to randomly select some samples among the women over 40 years. In this way, all the city's areas were covered. Inclusion criteria were women over 40 years, not already suffering from breast cancer, or having a family member (mother or sister) affected by the disease. Findings: The findings revealed that the high cost is the main barrier (20.1%) of mammography screening among the population. Among the other reasons, one may point to fear of discovering a cancer mass (9.5%), painful procedures of mammography (7.1%), not knowing the mammography centers (6.5%), and shame of undressing for mammography (5.1%). Comparing the mean scores of the barriers based on the individual characteristics showed that the barriers of mammography screening according to education level (p=0.0001), insurance status (p=0.02), and economic status (p=0.0001) have significant difference. Conclusions: Regarding the barriers of mammography screening among the Iranian women, it is necessary that authorities apply solutions to reduce costs, and promote women's knowledge about the importance of early diagnosis of breast diseases through screening plans, especially mammography screening.
Volume 7, Issue 4 (Fall 2021)
Abstract
Backgrounds: Evidence indicating the association of cancers and chronic inflammations is increasing. The importance of urinary tract and sexually transmitted infections (UTIs and STIs) in the development of prostate cancer is still unclear. Chlamydia trachomatis (C. trachomatis) is one of the most important causes of UTIs and STIs. Here, a case-control study was performed on the Iranian population to assess the association between C. trachomatis and prostate cancer (PC).
Materials & Methods: Paraffin-embedded prostate tissue specimens collected from 62 PC and 62 PBH (benign prostate hyperplasia) (as controls) patients were screened to detect C. trachomatis 16srRNA gene using nested polymerase chain reaction (nested PCR) method. A p-value < .05 was interpreted as a remarkable difference using SPSS statistical software Ver. 16.
Findings: There was a significant difference regarding the prevalence of C. trachomatis (p < .001; OR=10.07; 95% CI [2.81-36.001]) between the PC (33.87%) and BPH (4.84%) samples. Furthermore, prostate-specific antigen (PSA) levels were statistically higher (p< .05) in C. trachomatis-positive patients than in patients with negative C. trachomatis.
Conclusion: It could be concluded that patients with a history of C. trachomatis infections are more likely to develope PC. Therefore, early diagnosis and treatment of C. trachomatis infection may help the prevention of PC. Moreover, nested PCR is a suitable method for C. trachomatis detection in paraffin-embedded prostate tissue specimens.