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Aim: Most scientists are trying to treat cancer, and in this regard were produced numerous anticancer drugs, that adverse effects on non-target tissue. To overcome this, drugs freight to magnetic nanoparticles Chitosan and its carboxymethyl secondary coumpands are biopolymers that are non-toxic, biodegradable therefore found applications in biomedical field. We explain here that glycerol monooleate covered magnetic nanoparticles (GMO-MNPs) capable of transporting hydrophobic anticancer drugs. Method: In the present study, we have expanded 5-fluorouracil (5-FU) that loaded on chitosan MNPs for targeted cancer therapy. Results: The modified nano-adsorbent was then characterized by Fourier Infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), elemental analysis of CHN (9) and thermal weighing analysis (TGA). Lab conditions such as pH, contact time were optimized. To analyze the structure of the sample, X-ray diffraction spectroscopy was used to investigate the magnetic properties of the nanosized particles synthesized by the magnetometer and to detect the phase type formed on the monolayer glycerol matrix network using a polarizing light microscope. Also, the study showed essential oil release in the external environment of 90% for 30 hours. Conclusion: The optimized magnetic nanoparticles according to SEM image, exhibited segregated nanoparticles with sub-spherical smooth morphology and also the high thermal stability of 5-Fluorouracil nanoparticles which indicated a well-established structure of nanoparticles.

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Research subject: Saponin compounds have been considered as anti-cancer, antimicrobial, antifungal, anti-inflammatory, and antiviral activity agents. In addition, they are also used as foaming agents in some food industries. There are few studies for assessing the extraction of this substance, so far. The main purpose of this study is to assess and compare the extraction yield of Saponin by conventional extracting using solvent and super-critical fluid method.
Research approach: In the extraction with solvent, the effect of three independent parameters including mass of solid material, percentage of ethanol solvent, and time of extraction on process performance was investigated. Yield of extraction and Saponin concentration were considered as indexes for evaluating the process performance. In the super critical fluid extraction, the effects of extraction time, pressure, and temperature were investigated. In this method, carbon dioxide was used as super critical fluid and 80% ethanol was used as co-solvent. In order to design of experiment and process optimization, response surface methodology and central composite design was used.
Main results: In optimum condition of extraction with solvent, the mass of solid material, ethanol solvent percentage, and extraction time were 5.4 g, 77.5%, and 7 h, respectively. In this condition, the maximum efficiency of extraction yield of 1.12 mg of saponins per a gram of dry primary substance was obtained. The results indicated that time and solvent percentage were significant parameters.  Further, interaction between two factors of time and solvent percentage was significant. For supercritical fluid extraction, in optimum condition, extraction time, pressure, and temperature were 10 h, 400 bar, and 50 °C, respectively. Extraction yield in this condition was 20% more than the yield of conventional method. It is concluded that the supercritical fluid extraction method has higher performance than conventional method.

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Abstract
Research subject: The combustion of fossil fuels to supply energy produces large amounts of carbon dioxide. Carbon dioxide emissions have led to rising global temperature and many natural disasters, including floods, hurricanes, rising sea levels, and widespread droughts, that threaten ecological systems and human life. Therefore, the uptake and removal of carbon dioxide from sources or the environment play a key role in countering the threat of global warming.
Research approach: In this study, a venturi scrubber was utilized to eliminate CO2 from the air stream on a semi-industrial scale. The effects of different parameters including inlet air flow rate to the venturi scrubber, solvent flow rate, and solvent loss during the scrubbing process were investigated on CO2 absorption by a nanofluid solvent containing iron oxide/water at the presence of tetramethylammonium hydroxide (TMAH) as a surface-active material.
Main results: The surface-active material of TMAH prevents the agglomeration of nanoparticles in the base fluid and stabilizes the fluid. The maximum efficiency of absorption and the highest molar flux of CO2 were achieved when iron oxide nanoparticles were used along with graphene nanosheets with the ratios of iron oxide nanoparticles (25%) and graphene nanosheets (75%) at the presence of TMAH surface-active material due to their nature. The reason is the better agitation (of the solution) by iron oxide nanoparticles that results in an increased displacement of graphene nanosheets. The random Brownian movements of nanoparticles create micron size eddies that increase mass transfer at the gas-liquid interface. In addition, molar flux and CO2 gas absorption efficiency decreased by increasing the concentration of nanoparticles.
Keywords: Hybrid nanofluid; Venturi scrubber; Gas absorption; Iron oxide nanoparticles; Graphene nanosheets

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Nowadays, the importance of brand concept is so high that some researchers believe that brand is a perfect product and argue the most of the time customers instead of buying a product buy the brand. Therefore recognizing the factors influencing brand choice and investigating the specific features of brand is of   importance   and requires various studies .the present study aimed at investigating into factors that affect brand choice in food industrial companies . the methodology of this study was applied .research and for data collection. Survey approach was used. The statistical population consisted of buyers in Tehran and statistical sample based on factor analysis were 400 buyers.  Based on statistical analyses  , 19 factors that affect brand choice were categorized in 4classified:                   4 factors namely the simplicity of brand pronunciation, personality and psychological factor, recognition quality and services and  famous .further based on qualitative analyses based on qualitative analysis result revealed that "personality and psychological factor" for responding effects in brand choice to great extent    

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This paper discusses an adaptation of modal analysis concepts to time-varying periodic systems. It will be shown that the pseudo-modal parameters preserve certain properties of the conventional modal parameters defined for LTI systems. For this reason, after definition of pseudo modal parameters for time varying systems, a new modal analysis method will be introduced in time domain and it will be shown that these parameters could explain the nature of system. For periodic time varying systems, state transition matrices are formed by an ensemble set of responses which are obtained through multiple experiments on the system with the same time varying behavior. In next step the pseudo natural frequencies of a beam with moving mass using introduced method will be extracted. In final, it will be proved that for a linear time periodic system, the pseudo natural frequency treats periodic too.

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Nowadays the use of natural and biodegradable nanofibers in the packaging industry due to the contamination of non-biodegradable polymers in food packaging is dramatically obvious and electrospinning is one of the easiest ways to produce these nanofibers. In this study, the electrospinning of collagen polymer type I (extracted from the rat-tail) with Beta Cyclodextrin and Nanoclay was investigated and Acetic acid was used as a safe solvent in terms of the environment. After designing the experiments using an experimental design software (Design Expert 7.0), the effects of independent variables such as weight-weight ratio of Beta Cyclodextrin to Collagen (X₁), Volume-weight ratio of Nanoclay to Collagen (X₂) and solution feed rate (X₃) was evaluated on dependent variable, including nanofibers diameter (Y₁). Also, electrospinning process was performed with a voltage of 12 Kv and the distance between the needle and the collector 120 mm at ambient temperature and pressure. Nanoclay have been used due to barrier and antimicrobial properties; in addition, Beta cyclodextrin was used for the specificity of the structure that causes hydrophilic and hydrophobic surfaces. Furthermore, to investigate the shape of nanofibers Scanning Electron Microscopy, to investigate the structure Transform Infrared Spectroscopy, to investigate existing elements X-Ray Fluorescence Spectroscopy and to determine thermal resistance Differential scanning calorimetry was applied. The results showed that optimal nanofiber with a average size of 123.01 nm and a flawless structure with a viscosity of 145.33 mpa.s was obtained.

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Doogh is one of the most used fermented dairy drinks in Iran, whose durability and taste in the food industry is very important. The aim of this study was to investigate the antimicrobial effect of hydroalcoholic extract of salvia (Salvia officinalis), basil (Ocimum basilicum) and cinnamon on the durability of dough at ambient temperature.
Hydroalcoholic extracts of salvia, basil and cinnamon were extracted by maceration method. The antimicrobial effects of the extract of these three plants were determined by microdilution on yeast of Saccharomyces cerevisiae by determining minimum microbial inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), and then pH, acidity and antimicrobial effects of them in dough at ambient temperature over four weeks Checked out.
Based on the results of this study, the minimum inhibitory concentration of these extracts was between 6.25 and 12.5 mg/ml. Among studied extracts, salvia (Salvia officinalis), with a concentration of 0.62 mg/ml significantly decreased the yeast population of Saccharomyces cerevisiae in dough during four weeks (p<0.05). But basil (Ocimum basilicum) extract has only control effect and cinnamon extract has no antimicrobial effect.
Hydroalcoholic extract of salvia (Salvia officinalis), basil (Ocimum basilicum) and cinnamon can be used as an antifungal and antimicrobial agent as a natural preservative in dough and has an important role in consumer health.

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In this paper, a sandwich beam of a SMP material which have a corrugated core is studied. The corrugated core is from a polymeric material. Structures with corrugated profiles show higher stiffness-to-mass ratio in the transverse to corrugation direction compared to flat structures. As a result, the beam with corrugation along the transverse direction is stiffer than the one with corrugation along the beam length. The flexural behavior of the composite corrugated beam is studied employing a developed constitutive model for SMP and the Euler-Bernoulli beam theory. The constitutive model utilized is in integral form and is discretized employing finite difference scheme. To verify the results of the Euler-Bernoulli beam theory and finite difference method, finite element models of different corrugated sections have been simulated in a 3D finite element program. The results demonstrate that the developed model for the composite beam presented in this study predicts the behavior of the beam successfully. The sandwich beam with different corrugated cores (triangular, sinusoidal and trapezoidal shapes) are compared with each other. Also, results show that the shape fixity is decreased a little, like any other reinforcing method. This decrease in shape fixity results in increase of load capacity in composite beams. The stress-free strain recovery and constrained stress-recovery cycles are both studied.

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Study of different scouring areas relative to flow velocity in Downstream Base in pairs of bases and Impact of cable protection method on these areas Abstract Bridge failure is a common phenomenon all around the world. Bridges are one of the most important structures which are under attention from many years ago. Bridge is a structure to cross over obstacles such as rivers or valleys. Investigation of scouring in water structures especially in bridges is absolutely important in river engineering. Failure of several structures in all over the world are usually due to structural consideration and giant scales on piers. Created procedure of scouring by group of piers are more complicated than one single pier. Increasing the resistance of bed materials and decreasing the power of erosion factors are the ways to stand against local scouring. To decrease the power of erosion factors (horseshoe and wake vortex), equipment such as collars, submerged vanes and etc. are being used. This study was conducted with freshwater on cylindrical piers. The experiments were with a constant discharge during 6 hours in hydraulic laboratory of Ferdowsi University of Mashhad using a flume of 10 m length, 0.30 m width and 0.50 m depth. Sands with median diameter of 0.72, special gravity of 2.65 grams per cubic centimeters and geometric standard deviation of 1.12 are used in the experiments. Range of flow rate was from 8 to 18 l.s-1. An adjustable weir in the downstream regulates the water depth in the channel. The area for conducting the experiments in the channel has 1 m length and 10 cm bed height, which is 6 meters away from the beginning of the channel. Scouring procedure of downstream pier was investigated base on flow velocity. Results show that depth of local scouring of downstream pier can be categorized in 4 zone based on flow velocity: 1- No scouring occurrence zone, 2- Synchronized scouring zone, 3- Transitional zone, and 4- Deviance zone. Following previous investigations, effects of application of rolled cable over piers on reduction of scouring around two piers and zones of downstream pier (zones related to velocity) were examined. In this study, the efficiency of using rolled cable around the piers to decrease scouring is investigated. Results show that rolled cable, scouring will decrease. In fact, rolled cable around the piers will decrease the power of down flow, horseshoe and wake vortexes. Results show that scouring was reduced around piers due to application of rolled cable. So that cable at its best state reduces the maximum scour depth by 50 percent for downstream pier in the situation distance 3D and 54 percent for downstream pier in the situation distance 5D. Reduction of scouring depth of downstream pier was less than upstream piers. Scouring depth of downstream pier with rolled cable was 7 and 26 percent reduced in comparison with piers (No rolling cable was used) located at 3D and 5D from it. Because of scouring reduction as consequences of rolled cable, downstream zones were significantly changed that finally caused synchronized zone removal. Keywords: Local Scouring, Base group, Protective method, Downstream Base, Scouring zones

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Vegetables are perishable and cultivated seasonally. The aim of this study was to employ a combined thawing through hot air-infrared system, while investigating the effects of temperature, airflow velocity, and infrared radiation power on thawing time and the quality attributes of thawed carrots. In this research, carrot samples, having been washed and shaped using a cylindrical mold measuring 22.5 mm in diameter and 12 mm in height, were subjected to freezing at -18°C for 48 hours. Thawing parameters were air temperature (30°C and 40°C), airflow velocity (0.5  and 5 m/s), and infrared power (100 and 300 watts). The sample thawed at 25°C was control sample. Data analysis showed that reciprocal effect of increasing temperature, power of the radiation source and air flow speed had a significant effect on the thawing time, vitamin C, β-carotene, the thawing loss, and pH (P≤0.05). This system was able to significantly reduce the thawing time this time for the control sample was 47.66 minutes and for the shortest thawing time, the treatment 8 (F5P300T40) was 6.23 minutes. The lowest pH value was related to treatment 7 (F0.5P300T40) 5.81 and the highest value was related to treatment 1(F0.5P100T30) 6.15. The highest amount of β -carotene was related to treatment number 8 (F5P300T40) 48.12 mg/100g and  the lowest amount was related to treatment 5 (F0.5P100T40) 14.03 mg/100g. The highest amount of vitamin C was related to treatment 4(F5P300T30) 12.36 mg/100g and the lowest amount was related to treatment 1(F0.5P100T30) 3.68 mg/100g. . In the thawing loss, the highest amount was related to treatment 1 (F0.5P100T30) 19.7% and the lowest amount was related to the control sample7.44%. . Due to the low start-up cost, shorter process time and favorable quality, hybrid defrosting is widely used in the food industry.

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Archaeologically, the Roudbar plain is one of the richest and most outstanding regions in the south east of Iran. Tomb-e Kharg, is the largest site in this region. The site is a multi-period one, but based on the surface material, the main settlement belongs to the historical period. Some things remain unknown about these periods in south-eastern Iran and lack of any reference to them in the authentic authorities, makes this region necessary to be aimed of a particularly urgent archeological research as an underlying and reliable reference. To do this, a topographic map of the mound, as well as the grid map was laid out, in which the region was divided into 10×10m² regions. By means of simple random sampling method, 10% of the squares were then sampled. In the light of the study on the collected cultural material, the main settlement dates back to periods ranging from the first millennium BC up to the 8^th or 9^th AD centuries. Moreover, there are some items of painted grey ware, suggesting that this mound leads back to 3^th millennium BC.