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Background: Brucellosis is one of the most prevalent infectious diseases in Iran, which is shared between humans and animals. Brucellosis is caused by Brucella  species and transmitted via unpasteurized milk or dairy products, which has been reported at least in 80 countries.The present study aimed to evaluate the prevalence rate of seropositive cases of brucellosis in Yazd, Iran.
Materials and Methods: In this retrospective cross sectional study, seropositivity rate of brucellosis was examined for 12258 patients. The Wright test (1.80 or higher) was used for diagnosing brucellosis. The obtained results were statistically evaluated by chi-square which is a trend analysis method.
Results: The seropositivity rate of Wright test was reported to be 178 (1.5%), which was significantly higher in the summer (43.3%) and spring (29.7%) than other seasons (P = .000). It was also significantly higher in men (53.9%) (P = .000) than in women, and in people over 40 years (41%) (P = .000) than in other age groups.
Conclusion: Brucellosis seropositive studies provide very good information in order to help us in investigating the impact of brucellosis.

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Aims:One of the most important issues and challenges facing developing societies is the physical identity of buildings and urban facades. Cities, under the influence of modernity, have an identity problem, and the concept of urban identity in the process of cognition and perception presents a multi-dimensional and complex phenomenon. The physical identity of cities has become an influential category in city lifeThis article is based on the question that - How can a solution or a guideline be formulated to improve the formal identity and exterior appearance of architecture in the capital and a metropolis like Tehran, which is in line with today's tastes and intellectual level? Methods: The research method in this research is qualitative survey and research of applied type, and to answer the research question, first from the library method to examine the effective factors in the formation of physical identity, then through the questionnaire asked from the experts and professors of architecture. is placed

Findings: The statistical population consisted of 273 architecture professors, and finally, among the effective factors with the highest priority among the effective factors in the physical identity of the buildings, the combination of traditional and modern facades, the use of details and decorations in the facades, the use of sustainable materials, the spirit Nowadays, using the past model and paying attention to diversity and avoiding uniformity and homogeneity has had the greatest impact.

Conclusion: There are statistically significant differences between different respondents in their attitude towards facade parameters (mass and joint, openings, architectural details and materials). These results show the multiplicity and variety of trends in the practice of architecture for different jobs. It is also clear that the main reason for the significant difference between the averages is related to the fact that the respondents believe that these parameters had a significant impact on the continuity of the architectural identity.

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Objectives: Bordetella pertussis is a Gram-negative coccobacillus bacterium which is the causative agent of whooping cough. In recent years, the number of whooping cough cases has been rised. This bacterium has important virulence factors such as fimbriae and pertactin. In this study, polymorphism of Serotype 2 and 3 fimbriae genes and 2 Regions of pertactin gene were surveyed.
Materials & Methods: Totally, 20 B. pertussis clinical isolates were tested. DNA was extracted using the kit. Serotypes 2 and 3 fimbriae genes and pertactin Region 1 and 2 were identified using PCR method; finally, 13 samples were randomly sequenced.
Findings: No mutation was observed in the pertactin Region 2. In relation to the region1 of pertactin, 77% and 23% of the strains had prn2 and prn1 alleles, respectively. In relation to fim2 gene, 70% and 30% of the strains had fim2-2 and fim2-1 alleles, respectively. Also, in relation to fim3 gene, 70% and 30% of the strains carried fim3B and fim3A alleles, respectively.
Conclusion: In general, the present study results were similar to those of the previous studies conducted in Iran, but there were some differences in fim2 gene polymorphism so that the dominant allele changed from fim2-1 to fim2-2. Considering the fact that vaccine strains of Bp134 and Bp509 carry fim3A allele, which is different from the dominant circulating allele (fim3B), it is suggested that strains more similar to the dominant circulating strains should be used in designing vaccines.

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Objective: Among geographical regions, cities are increasingly becoming champions. Their competition to establish their reputation as the best choice for visitors, investors, and businesses is intensifying. Some cities possess unique features creating a distinct image in people’s minds. The present paper is aimed at identifying the most influential architectural components in city branding of Yazd and subsequently comparing and prioritizing them based on their impact.
Method: The research is conducted through using a questionnaire prepared for two groups: 1) a group of 35 specialists and 2) a group of 110 ordinary individuals. The snowball sampling method was used to select the sample for group 1, and random sampling method was employed for group 2.
Findings: This applied research is qualitative based on the nature of the data. All components were examined in both statistical populations using the SPSS test, revealing a significant impact on the city branding of Yazd. In terms of prioritization, the components’ degree of influence on the city branding of Yazd city differed between architects and urban planners as well as between ordinary people in two statistical populations.
Conclusion: Among ordinary individuals, the architectural texture had the greatest impact on the city branding of Yazd, whereas, among specialists, symbols and landmarks such as elements like windcatchers and awning had the most significant impact on this city’s branding.

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Aims: Today, the use of artificial intelligence has grown significantly, and is developing as a new field. The main goal of this research is to know the capabilities of artificial intelligence in advancing the design and implementation process in the artificial environment. The practical goal of research is the development and application of the most important achievements of machine learning in the field of design.
Methods: The main research method is "meta-analysis" research in the paradigm of "free research" with a critical approach and basic design, which examines the general knowledge field of this field using broad techniques. Then, to consolidate the literature on the topic, through searching three reliable knowledge bases of this field, we collected articles related to machine learning in the fields of unsupervised learning methods, semi-supervised learning, and reinforcement learning; The most important capacities and shortcomings, and strengths and weaknesses are reviewed.
Findings: Quantitative findings from the combined data indicate that supervised machine learning and directed deep learning can be the best option to recommend in the future of design. While the learning process in deep learning is gradual and slower, supervised machine learning works faster in the testing phase.
Conclusion: The research emphasizes that supervised machine learning is the best option for predicting answers in the design process. But if, in addition to prediction, the issue of creativity in design is desired, deep learning is more efficient.

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Aims:In the architecture of traditional houses, the environment used to be formed by the mutual interaction of human beings and nature. With the emergence of environmental crises in the contemporary world, the integration of natural and human processes became the most important ecological issue in the domain of sustainability. The aim of the current study is to recognize those ecological criteria of traditional houses which can be productive in the contemporary world so as to arrive at ecological solutions based on the thermal behavior of these houses in cold regions.
Methods:These factors are investigated in two traditional houses in Ardabil using descriptive methods, field observations, and quantitative analyses.
Findings:The investigation of the most critical climatic condition of the region is indicative of the thermal resistance of the rooms against temperature fluctuations. Furthermore, the analysis of the architectural features taken from physical environment (topography, climate) and structural environment (building form, spatial organization, material, landscape, infrastructure) shows that there is an optimal interaction between these components. The recognition of these architectural features can also provide ecological solutions.
Conclusion: The results of the assessment of the ecological criteria in the houses are also indicative of their conformity with the environment.In fact,these structures have overcome climatic effects via the use of natural resources in a way that rooms like shahneshin and basement which have seasonal function, have optimal performance against temperature fluctuations. For example, in a sample shahneshin room in smaller dimensions, the minimum difference between the inside and outside temperature is 13 °C

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Aims: Thermal comfort is one of the main factors for the participation of people in open urban spaces. This article focuses on the planting system in Jahan Nama Garden in Shiraz. The paper seeks to achieve the goal of reaching thermal comfort, increasing the people participation and optimization the outdoor thermal comfort in Jahan Nama garden.

Methods: The research method is descriptive-analytical and in terms of qualitative methodology. It used quantitative measurement in which the Jahan Nama garden has been simulated with ENVI-met 4. By selecting eight points in Jahan Nama Garden of Shiraz, climatic variables have been analyzed at 9, 12 and 17 o'clock on the 1st of July as the hottest day of the year. By comparing these points with the thermal comfort index PET they are analyzed.

Findings: Checking the plant simulation models (trees type and canopy and their number) in their place have improved the open space thermal comfort conditions, and by passing through the garden space, the environmental conditions return to the previous state and the average rate of radiant temperature has the greatest effect on thermal comfort, which will be presented in form of bar and line diagrams.

Conclusion: In planting system, increasing the number of trees has a greater effect on the thermal comfort in garden space. It is to boost the participation rate and the reduction of thermal stress in the hot seasons. The height and the form trees have direct effect on the thermal comfort.

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Aims: The centrality of spaces in architectural design, despite being considered as one of the pillars of aesthetics in traditional houses, has been neglected due to the current market-oriented view of the construction industry. The aim of this research is to develop a computational method to quantitatively explain the centrality in a traditional house for use in new buildings.

Methods: The spaces of traditional houses of the Qajar period were extracted and coded based on their spatial form and function. A computational model was presented to explain the deviation from the normalized center. The justified plan graph, spatial levels, and centrality of the spaces of the case study was drawn.

Findings: In the spaces of the traditional Imam Jome’s house, the courtyard, the veranda, the Shahneshin, the hall, the courtyard of the pond, and the inner courtyard represent centripetal spaces and have zero deviation from the center, and the outer courtyard with 14 connections is known as the most central space. On the other hand, the vestibule, the suffah, the ordinary rooms, the staircase, and the verandas were less central and were known as centrifugal spaces.

Conclusion: Examining centrality from both spatial and formal syntactic aspects, as well as validating with the help of mathematical calculations, can restore the pattern that existed in the architect's view at that time and use it in new buildings to highlight the aesthetic and functional elements of the building.