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In this research,nanocomposite coatings based on epoxy containing pristine graphene oxide and starch-modified graphene oxide are prepared and characterized by Fourier transfer infrared spectroscopy, andtheir crosslinking behavior is studied using nonisothermal differential scanning calorimetry.These nanocomposites, because of having platelet-like nanomaterials inside and their organic origin, can be applied as coating on metal surface in diverse industries.The reason behind using starch was its natural basis and abundance of hydroxyl groups in its structure which can take part in crosslinking reaction with epoxide. Neat epoxy systems having amine curing agent, and nanocomposites containing epoxy, amine curing agent, andpristine or starch-modified graphene oxide nanosheets were cure at different heating rates to assess their curing behavior. Change in hearing rate of test caused change in onset and peak temperature of the exotherm curves and consequently heat of reaction changed. It was observed that the presence of the graphene oxide nanosheets hindered the crosslinking reactions, while surface modification of them with starch natural polymer compensated for such a hindrance via catalytic role of starch, and increased crosslink density of system. 

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In this paper a node enrichment-moving error estimate and adaptive refinement procedure in Mixed Discrete Least Squares Meshless (MDLSM) method is suggested to improve the solution of elasticity problems. The suggested method uses of two node enrichment and node moving refinement procedures simultaneity. The voronoi diagram is used to locate the position of new added nodes in enrichment step. The errors of new added nodes, after each enrichment procedure, are calculated via interpolation rather than the error of simulation nodes to reduce the computational effort. So, the additional simulation effort saves and the steps of suggested method and conventional enrichment procedure are same. Completing the enrichment step, a node moving procedure is used to improve the solutions and solving the nodes excessive vicinity problem that is happened in conventional node enrichment procedure, especially with irregular node distribution. The node enrichment-moving method is continued to obtain the desirable accuracy. The proposed method is used to solve several examples and the results are presented and compared with those of conventional node enrichment procedure and analytical exact solutions. The results show superior efficiency, effectiveness and accuracy of the proposed method compared to conventional node enrichment method.

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​Distillates are one of the most popular consumer products of medicinal plants. High essential oil and low methanol contents have always been considered as two desirable factors by experts in the food and pharmaceutical industries. In order to investigate the effect of harvest height on Hyssop (Hyssopus officinalis L.) distillate quality, an experiment was conducted in a randomized complete block design with three replications. Four harvesting heights of 15, 25, 35 and 45 cm (measured from the highest point of the plant), as well as the remaining stalk, were the treatments in this research. The measured traits were: methanol and essential oil content in the distillates. The results of statistical analysis showed a significant effect of treatments on the studied traits. It can be said that methanol values significantly increased with the harvesting height measured from the top. It varied from 71.64 ± 2.7 mg/l for the height of 15 cm to 219.77 ± 3.52 mg/l for 45 cm. In the remaining stalk, methanol values increased from 142.33 ± 1.34 mg/l for 15 cm height to 393.86±24.65 mg/l for 35 cm height. It should be mentioned that at 45 cm height of cut, there was no remaining stalk. The amount of essential oil in the distillate increased with harvesting height. The findings of this study showed that the harvesting height of 15 cm from the highest part of the plant is recommended for obtaining a higher distillate quality with lower methanol content, and the possibility of increasing the number of harvesting cuts for the production of medicinal and nutritional products.

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Turn-milling is a new process that uses, turning and milling operations together, so that the tool and the work piece rotate simultaneously, for this reason, it has a wide ability in machining curved and complex surfaces. The Main subject of this research is Conducting research on the effect of changes in machining parameters, including work piece rotational speed, tool rotational speed and feed rate, on cutting parameters such as cutting force, cutting pressure, and surface finish parameters. The order and the number of experiments is designed based on the full factorial method. Experiments for each of the mentioned parameters were performed at three levels, which includes 27 tests in total. The results were analyzed with the help of Minitab software. The mentioned process was performed with a φ6 diameter end mill on a steel work piece 1.7225. As a result, increasing feed rate by three times increases the machining force by about two times and reduces the cutting pressure by about 27%, Also, the surface finish quality parameters R a  and R z  increased by 74% and 61%, respectively. The upward or downward trend of cutting forces, cutting pressure and the surface finish quality did not occur with the increase in the rotational speed of the work piece and the rotational speed of the tool, in fact, an extremum range was achieved in the increasing trend of the mentioned speeds. So that the minimum resultant force and also the cutting pressure were observed in the range of rotational speed of 950rpm of the tool and 300rpm of the work piece.

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Virus-based vectors, also called viral vectors are being studied in the field of gene therapy because of their innate biological and structural properties. Their ability to protect and specific delivery of genetic elements into the cells, promising results in the pre-clinical studies, going through clinical trials and approval of some products as a therapeutic option in some cancers introduce viral vectors as a powerful tool in the field of gene therapy. In this review, first an introduction about viral vectors is presented and then some studies about application of viral vectors in various fields of human diseases such as prevention and treatment are briefly discussed.