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Showing 2 results for Roshanravan


Volume 9, Issue 2 (Spring 2023)
Abstract

Backgrounds: Several studies have elucidated vitamin D as an important immunomodulatory factor regulating immune responses to different viral infections and vaccines. This study aimed to evaluate the impact of 25(OH) D serum levels on immune responses to hepatitis B virus (HBV) vaccine.
Materials & Methods: This study was conducted on 134 healthy individuals aged 18-35 years, referring to health centers for HBV vaccination in Mane and Samalghan city in North Khorasan, Iran from June to September 2021. Demographic data were collected through a questionnaire. Serum 25(OH) D levels were analyzed using commercial sandwich ELISA kits. Anti-hepatitis B surface antibody (anti-HBsAb) levels were determined in blood samples 4-6 weeks post-vaccination.
Findings: The prevalence of vitamin D deficiency and insufficiency among the participants was 46.3 was 34.3%, respectively. The level of 25(OH) D was insignificantly higher in women than in men. There was no significant association between serum 25(OH) D levels and participants' ethnicities and BMI ranges. Anti-HBsAb titer was significantly higher in participants with sufficient vitamin D levels compared to those with insufficient and deficient levels (1835 ± 252.55 vs. 1129 ± 120.7 and 1363 ± 0.125 ng/ml). Serum anti-HBsAb levels post HBV vaccination were significantly higher in women and younger individuals than in men and older individuals, respectively.  
Conclusion: This study findings suggest that participants with different serum vitamin D levels produce seroprotective antibody titers post HBV vaccination, while those with sufficient vitamin D levels may produce higher titers against HBV vaccine.
 

Volume 19, Issue 6 (June 2019)
Abstract

This paper presents a new method to design stabilizing and tracking control laws for a class of nonlinear systems whose state space description is in the form of polynomial functions. This method employs the nonlinear model directly in the controller design process without the need for local about an operating point. The approach is based on the sum of squares (SOS) decomposition of multivariate polynomials which is transformed into a convex optimization problem. It is shown that the design problem can be formulated as a sum of squares optimization problem. This method can guarantee of the nonlinear system with less conservatism than based Also, a sum of squares technique is used to evaluate the stability of closed loop system state with respect to exogenous input. The nonlinear dynamic model of air vehicles can usually be expressed by polynomial nonlinear equations. Therefore, the proposed method can be applied to design an air vehicle autopilot. The hardware in the loop (HIL) simulation is an important test for evaluation of the aerospace control system before flight test. The HIL results using designed controller for a supersonic air vehicle are presented. The results from HIL is compared to the software simulation that the appropriate consistency of results shows the efficiency of the proposed method in the air vehicle autopilot control loop.


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