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Aims: Vibrio cholerae is one of the intestinal gram-negative bacteria, causing cholera disease in developing countries; the two serogroups of O1 and O139 are the main causes of diarrhea. The bacteria resistance pattern to antibiotics varies in different countries. The aim of this study was to determine the resistance pattern of the isolates to representative antibiotics.
Materials & Methods: A total of 20 V. cholerae clinical strains were isolated from patients with cholera in Sistan and Baluchestan province of Iran during 2012-2013 outbreaks. After being identified by biochemical and molecular techniques, antibiotic susceptibility testing was performed for 6 antibiotics according to CLSI standards. Then, minimum inhibitory concentration (MIC) was also determined for tetracycline and erythromycin, using E-Test method.
Findings: All of the isolates were EL Tor biotype, O1 serogroup, and Inaba serotype. All of isolates were resistant to erythromycin and nalidixic acid, and 50% were resistant to tetracycline, while no resistance was observed against to ciprofloxacin, gentamicin, and ampicillin.
Conclusion: The sensitivity of all clinical isolates to antibiotics mentioned suggests that these antibiotics can likely be used in cholera disease treatment.

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Aims: Hepatitis B Virus (HBV) has infected more than million hundreds of people worldwide. Hence, a high rate of morbidity and mortality caused by liver-related diseases is due to HBV infection. However, a strong and effective treatment should be based on an accurate and correct diagnostic method. Hence, the present research provided a multidimensional study comparing and analyzing patients’ molecular and serological tests results.
Materials & Methods: In this research, the HBV DNA molecular tests results were studied by examining patients’ gender, age, and HBsAg strip results.
Findings: Among the female patients (29 persons) studied in this research, 55.1% were positive for HBV DNA and HBsAg strip tests, and 17.3% were negative for both tests. Also, among the male patients  (44 persons), 65.9% were positive, and 6.8% were negative for both tests.
Conclusion: The present study results shed light on the correlation between the HBV DNA and HBsAg tests. Also, the significance of HBV DNA tests was highlighted for particular diagnostic purposes and for the differentiation and interpretation of the pathophysiological conditions of patients with hepatitis B.