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Showing 2 results for Namdar Ahmadabad
Volume 9, Issue 2 (Spring 2023)
Abstract
Backgrounds: Several studies have elucidated vitamin D as an important immunomodulatory factor regulating immune responses to different viral infections and vaccines. This study aimed to evaluate the impact of 25(OH) D serum levels on immune responses to hepatitis B virus (HBV) vaccine.
Materials & Methods: This study was conducted on 134 healthy individuals aged 18-35 years, referring to health centers for HBV vaccination in Mane and Samalghan city in North Khorasan, Iran from June to September 2021. Demographic data were collected through a questionnaire. Serum 25(OH) D levels were analyzed using commercial sandwich ELISA kits. Anti-hepatitis B surface antibody (anti-HBsAb) levels were determined in blood samples 4-6 weeks post-vaccination.
Findings: The prevalence of vitamin D deficiency and insufficiency among the participants was 46.3 was 34.3%, respectively. The level of 25(OH) D was insignificantly higher in women than in men. There was no significant association between serum 25(OH) D levels and participants' ethnicities and BMI ranges. Anti-HBsAb titer was significantly higher in participants with sufficient vitamin D levels compared to those with insufficient and deficient levels (1835 ± 252.55 vs. 1129 ± 120.7 and 1363 ± 0.125 ng/ml). Serum anti-HBsAb levels post HBV vaccination were significantly higher in women and younger individuals than in men and older individuals, respectively.
Conclusion: This study findings suggest that participants with different serum vitamin D levels produce seroprotective antibody titers post HBV vaccination, while those with sufficient vitamin D levels may produce higher titers against HBV vaccine.
Volume 12, Issue 4 (Fall 2024)
Abstract
Aims: Health promotion standards focus on the needs of patients and their companions, serving as the foundation for fostering a healthy lifestyle for both patients and society. The present study aimed to determine the state of health promotion standards in educational hospitals affiliated with North Khorasan University of Medical Sciences using both internal and external evaluation methods.
Instrument & Methods: In this cross-sectional descriptive-analytical study, six educational hospitals affiliated with the North Khorasan University of Medical Sciences were recruited through census sampling. The World Health Organization’s self-assessment tool for health promotion in hospitals, which had been previously translated, localized, and validated, was used to collect data. This internal evaluation tool includeed four standards (management policy and program, health promotion of patients and families, health promotion of staff, and health promotion of hospitals and their surroundings) and 67 substandards. The internal evaluation team was selected from experienced hospital staff, while the external evaluation team was selected from the research team. They scored the status of each substandard from one to ten based on observations, documents, and interviews.
Findings: The internal evaluations revealed that hospitals made significant progress in health promotion standards, with a total average score of 7.05±2.25. The total average score of the external evaluation was 5.44±2.04, indicating that most evaluated hospitals were in the moderate stage of progress. In both internal and external evaluation results, the highest average score was related to the standard for health promotion of patients and families, while the lowest total average score was associated with the standard for health promotion of staff.
Conclusion: Educational hospitals affiliated with the North Khorasan University of Medical Sciences exhibit progress in health promotion but need improvement, particularly in staff health promotion.
