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Showing 2 results for Javadzadeh


Volume 7, Issue 4 (Fall 2018)
Abstract

This study was investigated growth indices, survival, and health parameters of Litopenaeus vannamei of 8.64±0.31gr, fed different diets 0, 0.5, 1, and 2% of powder garlic for 60 days. Results showed that weight, length and specific growth rate (SGR) of shrimp fed diets containing 2% of garlic powder (15.42gr, 16.2cm and 1.27%, respectively) significantly higher than other treatments (p<0.05), however, due to a significant increase feed conversion efficiency (FCE) in this treatment, the feed conversion ratio (FCR) is significantly reduced compared to other treatments (p<0.05). Also, because of stimulation of immune system, total haemocyte count (THC) and total plasma protein (TPP) were significantly increased (p<0.05) compared to other treatment, which leads to significantly increased survival rate of shrimp fed diets containing 2% garlic powder compared to shrimp fed diets containing 0.5 and 0% of garlic powder (p<0.05). According to these results adding 2% garlic powder to the diet of L. vannamei will lead to improving growth indices and increase non-specific immune system efficiency.


Volume 9, Issue 2 (Spring 2023)
Abstract

Backgrounds: Several studies have elucidated vitamin D as an important immunomodulatory factor regulating immune responses to different viral infections and vaccines. This study aimed to evaluate the impact of 25(OH) D serum levels on immune responses to hepatitis B virus (HBV) vaccine.
Materials & Methods: This study was conducted on 134 healthy individuals aged 18-35 years, referring to health centers for HBV vaccination in Mane and Samalghan city in North Khorasan, Iran from June to September 2021. Demographic data were collected through a questionnaire. Serum 25(OH) D levels were analyzed using commercial sandwich ELISA kits. Anti-hepatitis B surface antibody (anti-HBsAb) levels were determined in blood samples 4-6 weeks post-vaccination.
Findings: The prevalence of vitamin D deficiency and insufficiency among the participants was 46.3 was 34.3%, respectively. The level of 25(OH) D was insignificantly higher in women than in men. There was no significant association between serum 25(OH) D levels and participants' ethnicities and BMI ranges. Anti-HBsAb titer was significantly higher in participants with sufficient vitamin D levels compared to those with insufficient and deficient levels (1835 ± 252.55 vs. 1129 ± 120.7 and 1363 ± 0.125 ng/ml). Serum anti-HBsAb levels post HBV vaccination were significantly higher in women and younger individuals than in men and older individuals, respectively.  
Conclusion: This study findings suggest that participants with different serum vitamin D levels produce seroprotective antibody titers post HBV vaccination, while those with sufficient vitamin D levels may produce higher titers against HBV vaccine.
 

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