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In this study, the effect of fructooligosaccharide as a prebiotic on the growth and density of lactobacillus in intestine of stellate (Acipenser stellatus) has been investigated. To do this, 90 individuals of stellate fingerlings (ten in each replications) were prepared with an average weight of 30.16 ± 0.14 gr from International Sturgeon Research Institute. This study was carried out in a completely randomized design with three replications in fiberglass tanks with 2000 liters volume. They were fed with feed containing 0, 1 and 2 percents of fructooligosaccharide (Raftilos P95, Sigma Company). Results indicated that feed with one percent fructooligosaccharide had a significant effect (P < 0.05) on weight gain, SGR, FCR, FE, PER and HI. The number of colonies regarding to lactobacillus showed a significant increase compared to the control (in one percent fructooligosaccharide). Results indicated that fructooligosaccharide as a prebiotic (in level of one percent in feed) caused good growth capabilities and feed efficiency through increasing the density of lactobacillus in intestine.

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Background: Immunological factors are important in pregnancy loss because of the interaction between mother and fetus. T-regulatory cells as the component of humeral immune response play important role in the fetu-maternal interface. One of the regulatory mechanisms for these cells is mediated by antigen independent co-stimulatory signals and interaction of Cytotoxic T-Lymphocyte Antigen 4 (B7/CTLA-4) is one of these signals. The CTLA-4 which down regulates the activation and proliferation of T-cells occurs in a competitive interaction with CD28 to bind to B7. The aim of this study was to find out the relationship of CTLA-4 +49A/G gene with Recurrent Miscarriage in a group of Iranian women. Methods: In the present study, 60 women with the history of two or more pregnancy loss were selected and considered as the case group. A group of women (n=60) with at least two live births without any previous history of pregnancy loss and autoimmune diseases were taken as control group. Genomic DNA was extracted from whole blood using standard protocols. The CTLA-4 +49 A/G were detected using polymerase chain reaction-restriction fragment length polymorphisms assay. Results: The results showed that CTLA-4 +49 A/G polymorphisms were not significantly different in women with the history of two or more pregnancy loss compared to normal individuals. The frequency of G-allele polymorphism was 39.16% and 35.83% in patients and controls respectively. Conclusions: The data presented may suggest that the CTLA-4 is not associated with recurrent miscarriage in an Iranian population in Northwest region.

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An important subject in the field of linguistics is the impact of one thought system on the community of lingual symbols. The relationship between mind and language conventions has long been of interest to linguists. The importance of this relationship becomes more prominent in comparative approaches where, through comparative study and analysis of the main schemas of the ideas of several thinkers or artists, the researcher traces the consistent and common use of linguistic symbols. In the hermeneutic analysis of the works of Mowlana Jalal ad-Din Mohammad Rumi, the interpretation of symbols, analogy and codes governing his mind and language is a major research interest. One of the most important branches among these researches concerns the kinship of Mowlana’s language codes with other thinkers and artists. On the other hand, Nietzsche, as a transcendental thinker, tries to use a symbolic language in explaining his thinking system. Due to his familiarity with the culture and literature of the East and the essential sameness of some of his principles with Mowlana’s transcendental approaches about the existence, morality, art , etc., Nietzsche achieves a set of symbols common with Rumi, which forms a shared language between the two thinkers.  

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Research Subject: In this paper, the adsorbents used to remove lead ion using adsorption operation have been reviewed.
Research Approach: The types of adsorbents used to remove lead ions, the modifications of adsorbents, adsorption conditions, isotherms and adsorption capacity of adsorbents have been investigated and compared based on the literature survey.
Main Results: Modification by impregnation of functional groups has a significant role in increasing the adsorption capacity. The pH of the solution plays an important role in the adsorption of lead ions and generally the adsorption capacity increases by increasing the pH of the solution. Langmuir's isotherm model has been more consistent with the equilibrium data. Among the reviewed adsorbents, carbon-based adsorbents such as activated carbon and graphen-oxide, modified by chemicals such as ammonium persulfate or polyamines, show higher adsorption. Also, biomasses due to their abundance and low prices have the potential to be used as lead ion adsorbents.

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Intertextuality of two text: Comparative analysis between king Lear and Feridoon Comparative study which has opened to investigation the text could illuminate the relationship between cultures and shows the originality and richness of one literature alongside with range of its stubbornness of our or other culture. Comparative analysis between Feridoon’s tragedy and King Lear shows the interlocking relationship and arrangement between two texts in different and completely dissimilar culture and different historical context with two kind of language. Although mapping out the conscious or unconscious trace and impact of this texts over each other is completely impossible but the high level of intersexuality between the two texts is obvious so that this relationship could not be ignored. “similarity of plot”, “being tragically”, “impulses”, “familiarity of two text”, “dividing of kingdom”, “presence of destiny”, “parallel of characters”, “conflict”, “prediction”, “chorus” could be accepted as issues which are convinced common points between the two text. The analysis and survey toward understanding the equivalent between the two texts by helping of comparative literature is the fundamental question which has been followed by this paper.

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Among the recently collected chalcidoid wasps in a rice field of eastern Guilan province (coast of Caspian Sea), in July 2012, there was a specimen of Pteromalidae belonging to the genus Callitula. It was identified as Callitula ferrierei (Bouček, 1964). Both genus and species are new record for Iranian fauna. Morphological characters and geographical distribution of the newly recorded species are given.

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Projected global climate change may have a major influence on crop yield. The likely effects of climate change caused by increasing atmospheric carbon dioxide levels on rice yield in Iran were evaluated using a mechanistic growth model for rice, GSAC-rice, running under a climate change scenario predicted for a doubled-CO2 (2xCO2) atmosphere by the Geophysical Fluid Dynamics Laboratory (GFDL) General Circulation Model (GCM). Simulations were run for two locations with contrasting climates, one in the north (Rasht) and one in the south (Ahwaz) of Iran. GFDL predicted that as a result of doubling CO2 , temperature increases by 4.5 and 4.6 0C during the rice growing season in Rasht and Ahwaz, respectively. Changes in solar radiation are minor, but rainfall during the rice growing season decreases by 38.8% (102 mm) for Rasht and 68.2% (5.8 mm) for Ahwaz. It was predicted that doubling [CO2] alone increased rice yield by 30%, but that yield decreases by 3.7 and 11.6% for each degree centigrade rise in temperature in Rasht and Ahwaz, respectively. As a result of the combined effect of both doubling [CO2] and the climate change accompanying it (predicted with GFDL), 8% greater rice could be produced in Rasht, but irrigation needs would be increased dramatically by 57%. In Ahwaz (the south of Iran), rice production could be halved and might not even remain a viable option unless plant breeders are able to produce more heat tolerant rice cultivars. It was concluded that rice production in the north and south of the country would change dramatically.

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Angoumois grain moth, Sitotroga cerealella (Olivier) is one of the most important pests of stored products and known as factitious host for mass rearing of insect natural enemies. Effect of four commercial barely varieties including Fajr 30, Behrokh, Nik and Yousef on life table parameters of S. cerealella was determined at 26 ± 2 °C, 65 ± 5% RH and a photoperiod of 12:12 h (L: D). Data were analyzed based on the age-stage, two-sex life table theory. The results revealed that there were significant differences among various barely varieties regarding the developmental times, adult longevity and fecundity of S. cerealella. The longest developmental time (56.72 ± 0.29 days) was observed on Yousef. The longest and shortest male longevity were obtained on Behrokh (6.77 ± 0.27 days) and Yousef (5.79 ± 0.16 days). Moreover, female longevity ranged from 6.20 ± 0.18 to 7.23 ± 0.24 days on Yousef and Behrokh, respectively. The highest values of intrinsic rate of increase (r) were estimated 0.0719 ± 0.004 and 0.0717 ± 0.003 day^-1 on Fajr 30 and Behrokh, respectively and the lowest values were 0.0539 ± 0.004 and 0.0542 ± 0.003 day^-1 on Nik and Yousef, respectively. The longest generation time (T) was observed on Yousef. Furthermore, peaks of reproductive value occurred at ages of 45, 49, 48 and 53 days when reared on Fajr 30, Behrokh, Nik and Yousef, respectively. It can be concluded that Fajr 30 and Behrokh can be used for mass rearing programs of S. cerealella as an alternative host for natural enemies.

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SARAY" is part of the intangible heritage of the Azerbaijani people rooted in the culture, mentality and attitude of the people. So, it has been represented in oral literature, music, stories and poetry. In this study, the intangible cultural heritage is considered a cultural property, which pave the way to represent will, resistance and individual arguments of actual community activists to pass the crisis social and cultural contexts. The conceptual representation belongs to notion of Plato emerging in the idea and practice of recent intellectuals in the field of spiritual heritage which is now the main academic subject. This study was conducted qualitatively and has a descriptive and phenomenological research methodology. The purpose of this study is to investigate the permanent character of spiritual values or their representation in the urban life of the inhabitants of Ardebil by studying the spiritual heritage of Saray in the modern life of women in Ardabil. Intangible cultural heritage contains the historical, cultural, spiritual, scientific, and aesthetic values of current era, and can contribute to the growth and mobility of shared values and representations of values in everyday life. On the other hand, it refers to the existence of the culture of resistance and ethics of the region, and today it can be represented in the renewal of moral values, the commitment to the family for the present generations and future.

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Based on Mikhail Bakhtin’s point of view, the Dialogism, novel, more than anything else, is a linguistic phenomenon, which has a fair correlation between its genuine and its feature of heteroglossia. Language expresses the different social and ideological approaches of the utterances within a translinguistics framework. So the novel compiles all of these diverse social and ideological discourses and utterances. Different Character zones and discourses of the narrator, and embedded genres create a world of different voices and ideologies. From a feminist critique perspective (Gyno criticism), the novel Cheraghha ra Man Khamush Mikonam (I turn off the lights), applies social and cultural differences in different discourses to indicate the writer’s womanly standpoint through various social languages and utterences, and therefore, makes grounds for the promotion of the womanly voice in a multi-linguistic system. Here, through a descriptive-analytical method, we are going to study the “Heteroglossia” feature in the novel Cheraghha ra Man Khamush Mikonam written by Zoya Pirzad in the light of Bakhtin’s dialogism, and also from the Gyno criticism point of view, to analyze the diversity of discourses in this womanly novel. In this novel, the womanly awareness is indicated by the writer, the double-voiced discourse consists of the writer’s double-voice discourse and that of the narrator, embedded genres and the Character’s zones display the different social and cultural levels available, which also result in the appearance of a womanly world in the novel.

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Different attitudes in to the subject of translation have led to appearance of several topics in its extent, each of which has expanded the science of translation in different points of view and provided the grounds for its conversion into a separate field, entitled "translation studies". Among the many topics in this field, this article reviews the history of translation of the Holy Quran in terms of distinguishing between viewpoint and theory. In this regard, the issue of research is: what kind of view on the matter of translation is shown in the historical course of translation of the Qur'an? Studies on the evolution of the history of translations from the beginning of Islamic history to contemporary era, especially in Persian translations of the Holy Quran, shows that according to the definition of "translation theory", what happened in the history of translation of the Qur'an is more view pointing rather than a theoretical perspective. Of course, the existence of some successful theorizing in the historical course of the translation of Quran cannot and should not be ignored.
 

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Death" is the inevitable event of all humans. Some put it into oblivion, and some epistemologically accept it as reality and certainty. Investigating and analyzing the narratives of the two tyrannical, powerful and bloodthirsty characters in stories of Ferdowsi and Albert Camus and how they deal with their own and others' deaths is the main issue of this study. Caligula and Zahhak, who saw themselves as the absolute commander of the life and property of human, believed that they could also control death, trying to rid themselves of the fear of death by killing others, but nature faced with the phenomenon of death. How Ferdowsi (representing Islamic scholars) and Albert Camus (representing Existentialism) deal with the events of the story illuminates the philosophy of life and death from the standpoint of two thinkers in the East and the West. Both officials, after gaining power, commence unprecedented oppression and killing. Like all people in the world, they are scared to death and want to seize the power of nature to kill humans by killing them. Killing is the only way to combat the fear of death. The fate of both characters is similar, and eventually they are ousted from power due to murder and bloodshed against both rebels

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Backgrounds: Plasmodium vivax is one of the leading causes of malaria as a severe and death disease. Malaria has always been a major challenge for human health. The study of the genetic diversity of genes in malaria-causing agents has always been a concern for researchers. One of these genes is SERA, which plays a key role in parasite escape from the immune system.
Materials & Methods: DNA was extracted from 40 blood samples taken from symptomatic malaria patients infected with P. vivax in southern and southwestern Iran using a DNA extraction kit. Then PCR was performed with specific primers, and the data were analyzed by sequencing and recording genes.
Findings: In this study, 14 different isolates were identified among all samples, which were recorded in the World Gene Bank. The number of haplotypes among the 14 samples was 12. Also, there were 25 polymorphic nucleotide positions out of about 400 nucleotide sites. The ratio of non-synonymous to synonymous mutations (1.87094) and the amount of Tajima’s D (-0.57671) indicated the positive effect of natural selection on the genetic diversity of C-terminal region in the SERA5 gene.
Conclusions: Considering the safety and relative immunogenicity of vaccines, in addition to performing clinical trials, a regional vaccine should be developed to overcome genetic variation and antigenic changes in proteins.
 

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One of the most important stages of planning process (in all levels) is the evaluation of plans and programs. This process helps to improve plans, decision making and the possibility and reality of plans. Evolution can be accounted as an important factor in modifying the weak points in development plans and increasing the monitoring process. Rural development planning has recently encountered serious challenges such as: employment, participation of local peoples, increase of rural products, poverty alleviation, empowering individuals and trying to decrease regional disparities between the rural and urban areas. In Iran, various governmental organizations in rural areas have been active after the land reform and all of them tried to achieve their special goals. Social welfare organization is one of the most important organizations among them. This organization with its rural social welfare complex provides services to the rural residents. The present research attempted to study a rural welfare complex as a governmental organization and evaluate its role in rural development and social welfare of all villagers, specially the target groups. Therefore, the rural welfare complexes of Sojas, Karasf and Garmab in Khodabandeh suburb were studied using retrospective panel method and through measuring changes in time during T1 (before under coverage) and T2 (after under coverage). The analysis of the social- cultural and economic indicators showed that the function of these complexes are significant in the social affairs of the villagers and ensuring their basic need's compared with other factors α =%5.

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Phytophthora root and crown rot of soybean is known as a destructive disease of soy-bean both through out the world and in Iran. Physiologic races of Phytophthora soja were determined in this research and also a fast, accurate and simple method for inoculation of soybean to test race specific resistance. During the years　2001-4, infected soybean plants at different growth stages were collected from different areas and 22 isolates of P. sojae were recovered using PARPH medium. Physiological races of the pathogen were deter-mined on differential seedling lines by the hypocotyl inoculation method. Ten seedlings from each differential line grown in a 10-cm pot were inoculated under greenhouse condi-tions (25ºC) by a 10-14 days old fungus (LBA medium). The reaction of the seedlings was classified after 5-6 days as resistant (70% or more of seedlings alive) or susceptible (70% or more of the seedlings killed). Most isolates were identified as race one, six as race three, one as race four and one as a putative race 13. Race-specific resistance of the 60 cultivars towards race three was determined. Some of them such as ‘TMS’, ‘Maverick and ‘Williams 82’ were considered as resistant cultivars. All experiments were repeated three times.

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Objective: 22q11.2 chromosomal region is a hot spot for many cytogenetic rearrangements especially microdeletions which are responsible for DiGeorge and VeloCardioFacial syndromes. The most characteristic sign in these patients is congenital cardiac conotruncal anomalies. The gold standard diagnostic test for these microdeletions is FISH (Fluorescent In Situ Hybridization). However this diagnostic technique has some drawbacks such as high final cost and low sensitivity in smaller and uncommon microdeletions found in this region. The aim of this study was to introduce a less expensive and a priori more sensitive molecular method to help small and peripheral laboratories to find genetic causes of congenital heart diseases and DiGeorge syndrome. Materials and Methods: 10 patients with congenital conotruncal anomalies and symptoms of DiGeorge syndrome were included in this study. These patients had been analyzed by FISH probe TUPLE1 before the inclusion. 3 normal persons were included as normal controls for microdeletion region. Semi Quantitative Multiplex PCRs were designed based on known markers in and out of the region of intrest. Results were analyzed by TotalLab software. Results: 4 patients showed a decrease in gene dosage more than 60% compared to normal persons. FISH analysis found only one patient with microdeletion. Conclusion: The designed method based on semi quantitative PCR was able to find 4 patients (40%) with microdeletion in a population of 10 patients with congenital cardiac anomalies. This technique was also able to find microdeletions in three FISH negative patients. Molecular diagnosis of microdeletions is supposed to be more sensitive than FISH in small microdeletions. This study confirms the presence of atypical deletions in Iranian patients and shows that the applied technique can detect some FISH negative patients. However further studies are needed to determine the sensitivity and specificity of the mentioned molecular diagnosis. It seems that this can be used at least for the patients with typical phenotypic features of 22q11DS and negative FISH results.

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Objective: β-thalassemia is caused by absence or reduction of β-globin chain synthesis. One of the effective therapeutic methods for this disease can be gene therapy by viral vectors. The capacity of lentiviral vectors is approximately 8 kb, we designed a 6 kb construct containing mini LCR and β-globin gene instead of LCR region. The aim of this study is to make a recombinant lentiviruses containing miniLCR and β-globin gene for transfer to the target cells for gene therapy of β-thalassemia. Materials and Methods: HS2, HS3, HS4 segments (mini LCR) and β-globin gene with 5΄ and 3΄ UTR were amplified from the genomic DNA of a normal individual by PCR. Each segment was cloned in pTZ57R/T vector and then sub cloned first into the pBGGT vector and finally into the pLenti-Dest vector. Final transfer vector and the three helper packaging plasmids (Plp1, Plp2, Plp/VSVG) were cotransfected into 293T packaging cells using lipofectamine 2000. Harvested viruses were confirmed by RT-PCR on extracted RNA of these recombinant lentiviruses. Results: The titer of lentiviral stock determined in a K562 cell line and compared with COS-7 cell line. The titer in both cell lines was the same. Optimum MOI for COS-7 cell line was 5 and when polybrene was used transduction increased by 2 fold. The remaining transduced COS-7 colonies were expanded and DNA was extracted. By PCR, random integration of construct into the genome was evaluated. Conclusion: The produced lentiviruses can be an appropriate means for effective transfer of the designed construct into dividing and non-dividing cells such as hematopoetic stem cells for transplantation of beta thalassemia patients. Efficiency of transduction by leniviruses is more than the gene targeting technique. Also units of HS2, HS3 and HS4 regions in mini LCR and selection of larger HS3 unit may increase the expression of beta globin gene.