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This article begins with the presupposition that the idea of the Islamic Revolution was born in historical social context and intellectual and political currents 20s, so the problem, it is that How did the religious, intellectual and political in this decade? Which has provided social and historical context for the sociological phenomenon as the revolution.
In order to obtain ideas of the Islamic Revolution in separate thematic analysis of leader and elites Islamic Revolution thought and in this study whit the searching the religious, intellectual and political situation in 20s, achieved this result that Revolutionary thought is closer to one of the intellectual and political currents of the decade.
Whereof four major currents of thought and political had social life in the that tract  free space, after a brief mention of the status of that tract, will be discussed, to recognize these trends, but where of 57 Iran’s revolution have give Islamic indicating, most the focus of this article is to understand the ideas of the two branches of political Islamism, the religious fundamentalism and religious modernism in the 1320s. the religious fundamentalism is current that in the religious knowledge sees no need to change and is trying to extract answers all the questions and needs of modernity from religion in the from of pre-existing, not with a new understanding of religion, and religious modernism that includes a wide range, is trying to respond modernity to new understanding of religion that it leads to changes in religious knowledge in this paper is discussed in detail to the stream.

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Aims: Depression, anxiety, and psychiatric symptoms are more prevalent among women than men. Given the significance of depression literacy and its associated factors, this study aimed to explore the level of depression literacy and its correlation with depression stigma and attitudes toward seeking help among Iranian women attending health centers in Saveh City.
Instrument & Methods: This cross-sectional study assessed 280 women aged 18-65 selected through cluster sampling from September 2023 to December 2023 in Saveh County, Iran. Reliable and validated tools, including the D-Lit Questionnaire, Attitude Toward Seeking Professional Psychological Help Scale, and DSS-Personal Subscale were utilized for data collection. Data analysis was conducted using independent samples t-test and one-way ANOVA. Predictors were identified through hierarchical linear regression analysis.
Findings: The lowest correct answer rate was associated with knowledge of available treatment methods (15.4%). The mean scores for D-Lit, attitude toward seeking help, and personal depression stigma were 41.36±4.83, 23.63±3.69, and 25.39±4.36, respectively. Education level, consultation with a psychologist, attitude toward seeking help, and depression stigma collectively accounted for approximately 23% of the variance in depression literacy.
Conclusions: The level of depression literacy among Iranian women is insufficient.

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Introduction: Gentamicin (GM) is a widely used aminoglycoside antibiotic. The nephrotoxicity of gentamicin causes reducing renal blood flow via vasoconstriction. Given PGE2's vasodilatory effects and the mechanisms of tissue damage in GM-induced nephrotoxicity, such as vasoconstriction, the aim of this study was to investigate the protective role of PGE2 in GM-induced nephrotoxicity. The diclofenac sodium was used to assess the direct effects of exogenous PGE2 by blocking endogenous production.
Materials and methods: The experiment was conducted on 56 male Wistar rats (200–250 g). Renal nephrotoxicity was induced by intraperitoneal (i.p.) injection of gentamicin (100 mg/kg). The therapeutic effects of PGE2 (0.2 µg/kg) and diclofenac (0.5 mg/kg) were assessed. The rats were placed in individual metabolic cages to collect urine. The systolic blood pressure and renal blood flow were measured. Levels of urea, creatinine, sodium, potassium, magnesium, and osmolarity were analyzed in plasma and urine samples. The left kidney was used for histological analysis.
 Results: Administration of gentamicin for eight consecutive days resulted in a significant increase (p<0.001) in serum creatinine, blood urea nitrogen (BUN), absolute sodium excretion (UNaV), and fractional excretion of sodium and potassium (FENa and FEK), while creatinine clearance, urine osmolarity, and renal blood flow significantly decreased (p<0.001) compared to the control group.
Treatment with PGE2 significantly reducing serum creatinine, UNaV, FENa, FEK (p<0.001), and BUN (p<0.05), while significantly increasing creatinine clearance, urine osmolarity, and renal blood flow (p<0.001).
Conclusion: Prostaglandin E2 provided substantial protective effects against gentamicin induced acute nephrotoxicity in rats.