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The toxicity in organizations has became a pervasive phenomenon in everyday organizational life. Since, investigating and recognizing the nature and identity of toxic organizations have drawn attention of theorists and researchers to itself. In this regard, the purpose of this study is designing the interpretive structural model of toxic organization’s consequences. For this purpose, after studying literature and identifying consequences of toxic organizations, a half-closed questionnaire embodied consequences was developed based on Likert scale and distributed among 26 experts from administrative organizations in Rafsanjan, using concept and snowball sampling. Based on fuzzy analysis, the questionnaires statements were screened. Then, the other identified consequences of toxic organization were screened and after categorizing consequences of toxic organization, the measure for ISM were developed and distributed among mentioned experts. Finally, data were analyzed and interpretative structural model of studied phenomenon were drew. The model possessed 6 variables in 3 levels (the first level: cognitive, psychological-attitudinal, behavioral, and group consequences; the second: inter-organizational consequences; the third: outer-organizational consequences).

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One of the problems related to oil recovery is water production, which reduces the production life of oil reservoirs and wells. Nowadays, the polymer gel injection method is used to control water production in the reservoir. In this study, an attempt has been made to investigate the rheological properties of xanthan-based hydrogels, considering Iran's reservoirs and also due to the existence of environmental problems in the field of synthetic polymers. The strength and stability of hydrogels can be applied by changing environmental conditions as a function of time and shear rate. For this purpose, the viscoelastic properties of hydrogels, including the elastic and viscous modulus, have been studied in relation to temperature, time and deformation rate for the gelant solution. Also, the effect of the composition of hydrogels, including the polymer concentration, the weight ratio of the crosslinking agent to the polymer, and the weight percentage of silica nanoparticles was considered in the study of rheological properties. Additionally, gelation time has been studied as one of the most important determining parameters of hydrogel during injection in porous medium. 

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ntroduction: Colorectal cancer (CRC) is one of the most important cancers and the second leading cause of cancer mortality in Iran. CRC is spread through genetic and epigenetic changes. Understanding the molecular pathways in these genetic and epigenetic changes can provide a clear perspective on cancer treatment.
Materials and Methods: This study was performed on 40 samples of intestinal tumor growths (polyps), 30 tumor samples and 40 normal tissues adjacent to the tumor. RNA and tissue DNA extraction, study of gene expression, miR-22, miR-194 LncRNA MINCR using Real time PCR was performed.
Results: In this study, the expression of MINCR LncRNA in tumor and polyp samples increased compared to the adjacent normal tissue and the expression of miR-194 miR-22 was decreased. Negative correlation coefficient was observed between miR-22, miR-194 and MINCR expression levels and also a significant relationship was observed between the expression of these lncRNAs and microRNAs.

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Samples of grass pea seed (Lathyrus sativus) were prepared and analyzed for some chemical composition and as well for their anti-nutritional factors. The rumen degradability coefficients and post ruminal digestibility of dry matter and crude protein of unheated vs. oven heated samples were determined, employing in situ and in vitro techniques. Results indicated that grass pea seed contained a considerable level of crude protein (36%). The process of heating reduced (P< 0.05) tannins and Oxalyl DiAminoPropanoic acid (ODAP) content in grass pea seeds. Heat processing, especially 3 hours of heating, increased (P< 0.05) the slowly degradable fractions of the seed. Ruminal disappearance of DM and CP occurred at a lower rate (P< 0.05) for the heated grass pea seed than for the unheated seed. Heat processing did not affect the production of some such nutritional parameters (estimated through gas production method) as DOM, ME, NE_L, SCFA and MP production (P> 0.05). It was concluded that grass pea seed was of a substantial potential as a protein source in ruminant nutrition with its heat processing resulting in positive effects on its DM and CP digestibility.