Khodabandehlu, Fatima, Soheili, Shahram, Parsian, Heshmatolah, Ershadi, Rouhallah, Azarbayjani, Mohammad Ali (2025). The effect of CX training on endothelial microparticles and nitric oxide in women with metabolic syndrome. , 28(1), 65-70.
Fatima Khodabandehlu; Shahram Soheili; Heshmatolah Parsian; Rouhallah Ershadi; Mohammad Ali Azarbayjani. "The effect of CX training on endothelial microparticles and nitric oxide in women with metabolic syndrome". , 28, 1, 2025, 65-70.
Khodabandehlu, Fatima, Soheili, Shahram, Parsian, Heshmatolah, Ershadi, Rouhallah, Azarbayjani, Mohammad Ali (2025). 'The effect of CX training on endothelial microparticles and nitric oxide in women with metabolic syndrome', , 28(1), pp. 65-70.
Khodabandehlu, Fatima, Soheili, Shahram, Parsian, Heshmatolah, Ershadi, Rouhallah, Azarbayjani, Mohammad Ali The effect of CX training on endothelial microparticles and nitric oxide in women with metabolic syndrome. , 2025; 28(1): 65-70.

The effect of CX training on endothelial microparticles and nitric oxide in women with metabolic syndrome

Pathobiology Reserach
Article 6, Volume 28, Issue 1, 2025, Pages 65-70    PDF (292.42 K)
Document Type: Original Research
Authors
Fatima Khodabandehlu1; Shahram Soheili* 2; Heshmatolah Parsian3; Rouhallah Ershadi4; Mohammad Ali Azarbayjani5
1Ph.d Student ofnDepartment of Exercise Physiology, Kish International Branch, Islamic Azad University, Kish Island, Iran.
2Department of Physical Education and sport science, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran
3Assistant professor of Department ofPhysical Education and sport science, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran.
4Assistant professor of Department of Physical Education and sport science, Bushehr Branch, Islamic Azad University, Bushehr, Iran.
5Professor of Department of Physical Education and sport science, Tehran Center Branch, Islamic Azad University, Tehran, Iran.
Abstract
Introduction: Endothelial dysfunction is a consequence of obesity and metabolic syndrome. In this study, the effect of CX Works training (CX) on serum endothelial microparticles (EMPs) and nitric oxide (NO) as markers of vascular endothelial function was measured in women with metabolic syndrome.

Methods: For this purpose, 24 sedentary adult obese women were randomly divided into CX (8 weeks, n= 12) and control (no training, n = 12) groups. CX were performed every other day for 8 weeks. Serum NO and EMPs after an overnight fast were measured in both study groups (pre-training) and measurements were repeated 48 hours after the last CX training session (post-training). Independent / paired t-test was used to compare between groups.

Results: CX training resulted in significant increase in serum NO and decrease in EMPs compared to the pre-training (p<0.05). No significant change were observed in any variables in control groups (p>0.05).

Conclusion: CX training, as a novel exercise modality, is associated with improved vascular endothelial function in women with metabolic syndrome. Measurement of other vascular markers is needed to better understand the mechanisms responsible for these changes.
Keywords
CX training; Metabolic syndrome; Nitric oxide; Endothelial microparticles
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