Dolatyar, Ali Reza, Dalimi Asl, Abdolhosein (2006). A study on the clinical symptoms, eosinophil and serum immunoglobuline alterations in the patients infected with Giardia lamblia. , 8(1), 13-18.
Ali Reza Dolatyar; Abdolhosein Dalimi Asl. "A study on the clinical symptoms, eosinophil and serum immunoglobuline alterations in the patients infected with Giardia lamblia". , 8, 1, 2006, 13-18.
Dolatyar, Ali Reza, Dalimi Asl, Abdolhosein (2006). 'A study on the clinical symptoms, eosinophil and serum immunoglobuline alterations in the patients infected with Giardia lamblia', , 8(1), pp. 13-18.
Dolatyar, Ali Reza, Dalimi Asl, Abdolhosein A study on the clinical symptoms, eosinophil and serum immunoglobuline alterations in the patients infected with Giardia lamblia. , 2006; 8(1): 13-18.

A study on the clinical symptoms, eosinophil and serum immunoglobuline alterations in the patients infected with Giardia lamblia

Pathobiology Reserach
Article 3, Volume 8, Issue 1, 2006, Pages 13-18    PDF (197.13 K)
Authors
Ali Reza Dolatyar1; Abdolhosein Dalimi Asl* 2
1Graduate Department of Parasitology, Tarbiat Modares University, Tehran, Iran.
2Department of Parasitology, Tarbiat Modares University, Tehran, Iran.
Abstract
Purpose: In the present work, clinical symptoms, serum immunoglobuline alteration and eosinophil count were investigated in the patients infected with Giardia lamblia.
Materials and Methods: In this regard, 50 persons infected with Giardia and 50 healthy individuals were selected as the study and control groups respectively in Tehran. Sera of the groups were tested for IgG, IgE, IgA levels and their blood for the percentage of eosinophil. To measure IgA and IgG levels the SRID technique and to measure IgE level the ELISA technique were applied.
Results: Results indicated that, 78%, 74%, 60%, 58% and 12% of the patients showed diarrhea, abdominal pain, weight loss, flatulence and visual disorder respectively, while no aforementioned symptoms were observed in non-infected individuals. In addition, the mean of eosinophil percentage as well as IgA, IgG and IgE levels in the infected group were found to be higher than that of the non infected group significantly (P<0.05). Meanwhile, no elevation was observed in the eosinophil percentage or immunoglobuline levels of the control group.
Conclusion: In conclusion, Giardia lamblia can induce eosinophila and increase the level of IgE in the infected patients significantly.
Keywords
Giardia lamblia; Clinical symptoms; Eosinophil; Serum Immunoglobuline
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