Emergence of Vancomycin-Resistant Staphylococcus aureus in the Southwest of Iran | ||
| Infection Epidemiology and Microbiology | ||
| Article 2, Volume 5, Issue 4, 2019, Pages 9-16 PDF (396.4 K) | ||
| Document Type: Original Research | ||
| Authors | ||
| Vedad Al-Khamis; Seyedeh Elham Rezatofighi* ; Hossein Motamedi | ||
| Department of Biology, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Iran | ||
| Abstract | ||
| Aims: Following the emergence of methicillin-resistant Staphylococcus aureus (MRSA) isolates, the use of other antibiotics especially vancomycin in S. aureus infections has become inevitable, leading to the emergence of vancomycin-resistant S. aureus (VRSA) strains, which is considered as a major public health concern. This study aimed to determine the vancomycin susceptibility patterns of S. aureus clinical isolates in order to evaluate the current status of vancomycin resistance in the southwest of Iran. Materials & Methods: In this study, 100 S. aureus clinical strains were collected from the hospitals of Khuzestan province in the southwest of Iran. Next, antibiotic susceptibility, vancomycin resistance, and the presence of mecA, vanA, vanB, vanC, and vanD genes were investigated in these isolates. Findings: It was found that 1 and 2 isolates were vancomycin-intermediate S. aureus (VISA) and VRSA, respectively. All three strains showed methicillin-resistance pattern and carried mecA gene. vanA gene was detected in VRSA strains, whereas vanB, vanC, and vanD genes were detected in none of these isolates. Conclusion: This study findings could be alarming regarding the emergence and spread of VRSA strains; therefore, the principles of infection control should be employed in the healthcare systems to prevent the spread of VRSA strains in healthcare facilities. | ||
| Keywords | ||
| Vancomycin; Staphylococcus aureus; Antibiotic resistance; Methicillin-resistant Staphylococcus aureus | ||
| References | ||
|
| ||
|
Statistics Article View: 100 PDF Download: 73 |
||
| Number of Journals | 45 |
| Number of Issues | 2,174 |
| Number of Articles | 24,684 |
| Article View | 25,075,736 |
| PDF Download | 17,776,201 |